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Stem Cell research finally begins to pay off - 4/11/2007 9:44:04 PM   
luckydog1


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I am surprised to not see a thread on this yet.  Researchers have used a stem cell therapy to really treat Type I diabetes. http://www.sciam.com/article.cfm?alias=stem-cell-transplant-prom&chanID=sa003&modsrc=reuters  Out of the 16 in the trial, 15 responded positivley.  14 patients became insulin-free -- 1 for 35 months, 4 for at least 12 months, and 7 patients for at least 6 months. Two "late responders" were insulin-free for 1 and 5 months, respectively.  Even if it meant a shot once a month it would be a godsend for people with this disease. 

The real kicker is that they were not embryonic cells, they were taken from the individuals, so we dont have to kill semi babies to get them. 
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RE: Stem Cell research finally begins to pay off - 4/11/2007 9:53:11 PM   
minnetar


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That is wonderful news.  this girl does the transplant claims and loves to see the good.

minnetar

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RE: Stem Cell research finally begins to pay off - 4/11/2007 10:06:02 PM   
cynthiamarie


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Just talking to myself, but...I wonder why they had to use an immune system suppressant for these people to receive their own stem cells back. 

Diabetes runs rampant in my family, but it's type 2 and I don't have it *knocks on wood*.  Three out of 15 having some major complication come up, ouch.  This sounds promising but I hope the odds go up.


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RE: Stem Cell research finally begins to pay off - 4/11/2007 10:06:48 PM   
Devilslilsister


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Good stuff.  Cord blood is awesome too.........  i'm actually researching right now if it will help cure my mother of lupus.  We're going to bank it anyways..........  and it technically should cure her, but so far i havent found anything that says it does.

but it SHOULD


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RE: Stem Cell research finally begins to pay off - 4/11/2007 10:14:19 PM   
luckydog1


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cynthia, I beilieve it was the process of harvesting the cells weakens the immune system out for a few days, making them susceptible to infection.  I would assume they will get better at dealing with that.

Devils lil, I would certainly bet the placental blood will be usefull for something, and I would imagine the closer genitcally the cells are the better( IE from close family).

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RE: Stem Cell research finally begins to pay off - 4/11/2007 10:20:56 PM   
Devilslilsister


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Lucky - they are good for ALOT of thigns actually......  i just cant find anything related to lupus.  Its not actually, or technically from the placenta.. but rather the umbilical cord. 

Here's a list of treatable diseases

http://www.viacord.com/treatable-diseases.htm

and i dont understand why Lupus isnt listed under "immunodeficiences"

::sigh:: it should be. 


< Message edited by Devilslilsister -- 4/11/2007 10:22:23 PM >


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RE: Stem Cell research finally begins to pay off - 4/12/2007 2:12:03 AM   
Vendaval


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General reply -
 
I posted about this in the Health and Safety section today.
Also, the House and Senate have approved a new bill
for stem cell research funding, but Bush is promising to veto it.

 
"Stem cell bill approved by Senate"


By DAVID ESPO, AP Special Correspondent Wed Apr 11, 7:24 PM ET
 
"WASHINGTON - A stubborn Senate voted Wednesday to ease restrictions on federally funded embryonic stem cell research, ignoring  President Bush's threat of a second veto on legislation designed to lead to new medical treatments."
 

http://news.yahoo.com/s/ap/20070411/ap_on_go_co/stem_cells;_ylt=AkPQtL2HS50VmsGmnEcWYnwPLBIF

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RE: Stem Cell research finally begins to pay off - 4/12/2007 2:20:54 AM   
ownedgirlie


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There was a rather heated thread last Oct/Nov on stem cell research, in which I repeatedly asked if a medical issue could be resolved by umbilical cord stem cells, would people use that over fetal stem cells.

No one seemed to want to answer that question; they seemed to want to argue it instead. 

I am very glad to see this news, and to see a case proven that we can indeed make medical progress this way.  So many will benefit from it, all the way around.  Great news indeed :)

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RE: Stem Cell research finally begins to pay off - 4/12/2007 2:55:27 AM   
Vendaval


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It is very frustrating when people would rather argue than
find facts, owned girlie.
 
Wikipedia has a basic explanation of what is involved in the
research, potentials for treatment, and the arguments for
and against. 
 
http://en.wikipedia.org/wiki/Stem_cell_research
 
http://en.wikipedia.org/wiki/Embryonic_stem_cell
 
http://en.wikipedia.org/wiki/Adult_stem_cell
 
http://en.wikipedia.org/wiki/Stem_cell_treatments

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RE: Stem Cell research finally begins to pay off - 4/12/2007 6:31:20 AM   
Devilslilsister


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I actually think that umbilical cord stem cells is all our medical field should need.  They've already made amazing progress in the area and its just in the begining stages.  When i looked into it years ago, there was ALOT less on the list of treatable diseases.  

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RE: Stem Cell research finally begins to pay off - 4/12/2007 7:25:06 AM   
pahunkboy


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i heard aalot of promising stuff is in the pipeline.

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RE: Stem Cell research finally begins to pay off - 4/12/2007 10:03:57 AM   
ownedgirlie


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Thank you, Vendeval.  The National Health Institute has a lot of material on the subject as well.  It is amazing what progress is being made.

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RE: Stem Cell research finally begins to pay off - 4/12/2007 9:14:18 PM   
Sinergy


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quote:

ORIGINAL: cynthiamarie

Just talking to myself, but...I wonder why they had to use an immune system suppressant for these people to receive their own stem cells back. 

Diabetes runs rampant in my family, but it's type 2 and I don't have it *knocks on wood*.  Three out of 15 having some major complication come up, ouch.  This sounds promising but I hope the odds go up.




The immune system can sometimes get confused and begin attacking it's own cells...

I suspect it is done in case the body decides it doesnt trust undifferentiated stem cells.

Sinergy

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RE: Stem Cell research finally begins to pay off - 4/12/2007 9:17:56 PM   
Sinergy


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quote:

ORIGINAL: ownedgirlie

There was a rather heated thread last Oct/Nov on stem cell research, in which I repeatedly asked if a medical issue could be resolved by umbilical cord stem cells, would people use that over fetal stem cells.

No one seemed to want to answer that question; they seemed to want to argue it instead. 

I am very glad to see this news, and to see a case proven that we can indeed make medical progress this way.  So many will benefit from it, all the way around.  Great news indeed :)


I responded to that thread a number of times, ownedgirlie.

The point I made was that umbilical stem cells have not been found in research to be as effective as fetal stem cells for certain uses.

This is not technically an argument.

Sinergy



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RE: Stem Cell research finally begins to pay off - 4/12/2007 11:43:30 PM   
ownedgirlie


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You would not answer the simple question of whether or not umbilical cord stem cells were worth discussing, and instead repeatedly asked me to defend my case, of which I had made none.

You also proposed that I would let my own children die simply to avoid fetal stem cell work.  I found that appalling, argumentative, and not at all related to the topic I had proposed to discuss.  I will not be going down that road with you again.

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RE: Stem Cell research finally begins to pay off - 4/13/2007 9:11:35 AM   
luckydog1


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But these are stem cells taken from the bone marrow, not umbilical or embryonic.

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RE: Stem Cell research finally begins to pay off - 4/13/2007 10:16:18 AM   
ownedgirlie


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They were, yes, and I neglected to include that type of stem cell in my post.  My earlier point was embryonic vs. non-embryonic and whether or not medical advances could be made with the latter, without having to rely on the former. 

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RE: Stem Cell research finally begins to pay off - 4/13/2007 10:59:31 AM   
DomKen


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There is some serious misunderstanding of this treatment.

The 15 people were all recently diagnosed with Type I diabetes. In these people their immune system had for some reason started attacking the cells that made insulin. The treatment involved chemotherapy to kill off the persons immune system after stem cells involved in immune system growth had been harvested. Then the stem cells were introduced with the hope that some insulin producing cells survived and would regenerate and that the regenerated immune system would go back to ignoring the insulin producing cells.

This treatment is therefore very risky and only effective in otherwise healthy people who are diagnosed with Type I diabetes very early in the progression of the disease.

It should also be noted that in a patient with more advanced type I diabetes the pancreatic cells that make insulin are completely wiped out and some source, like fetal stem cells, would be needed before this sort of treatment could even be attempted.

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