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Recent diminished painkiller effect... - 3/11/2013 9:52:24 PM   
Duskypearls


Posts: 3561
Joined: 8/21/2011
Status: offline 		Anyone else out there finding the amounts they normally take are either hardly, or not at all, effective?

Anyone else taking their usual amounts of daily pain meds, yet suddenly finding their body/nerves going through withdrawal each day?

Don't know what the heck's going on with me. In regards to narcotics, my liver's always processed them 2-3 times faster than other humans, but this is bloody ridiculous!

Maaaannn, I am SO uncomfortable. It's like every day, going through cold turkey, so that I must take even more than usual to abate that discomfort. I dunno, the whole world seems kukamunga lately.

I've had years of experience with different narcotic painkillers, and this is a first for me.

< Message edited by Duskypearls -- 3/11/2013 9:54:34 PM >
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RE: Recent diminished painkiller effect... - 3/11/2013 9:56:43 PM   
Lynnxz


Posts: 4813
Joined: 10/3/2006
From: Atlanta
Status: offline 		Building up a tolerance is pretty typical for narcotics.

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RE: Recent diminished painkiller effect... - 3/11/2013 9:59:43 PM   
Duskypearls


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quote:

ORIGINAL: Lynnxz

Building up a tolerance is pretty typical for narcotics.


Good idea, but nope, it's not a tolerance issue. I should have thought to mention that from the git go. Any other ideas?

< Message edited by Duskypearls -- 3/11/2013 10:12:33 PM >

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RE: Recent diminished painkiller effect... - 3/11/2013 10:14:46 PM   
TAFKAA


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Status: offline 		What exactly are you taking?

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RE: Recent diminished painkiller effect... - 3/11/2013 10:23:43 PM   
Duskypearls


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quote:

ORIGINAL: TAFKAA

What exactly are you taking?


Percocet w/acetominophen.

There have been great changes in my life, recently, in regards to mental, emotional, spiritual aspects, as well as work and how I output energy there. Most unusual is a tremendous increase in psychic experiences, in terms of their frequency and nature.

I seem to nearly be a completely different person than I was 4 months ago, using tremendous amounts of energy, on all of the above-mentioned aspects. There is a HUGE spiritual change going on in me.

I do not know what else to attribute it to. As I said, I've had years of experience w/such drugs, including tolerance issues and actual cold turkey withdrawal issues, tho' not on a daily basis when I'm presently taking between 40-100 mg/day.

It's terribly difficult for me to describe how different the recent drug inefficiency aspect is. Wish I could do better. I would normally take 40-60 mg/day, and that would do the trick. Now, even 100mg, even in one dose, doesn't have any effect, and then there's withdrawal symptoms on top of it. That should not be. Something wierd's going on.

< Message edited by Duskypearls -- 3/11/2013 10:24:32 PM >

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RE: Recent diminished painkiller effect... - 3/11/2013 10:27:58 PM   
Lynnxz


Posts: 4813
Joined: 10/3/2006
From: Atlanta
Status: offline 		10-325? Hopefully?

< Message edited by Lynnxz -- 3/11/2013 10:28:08 PM >

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RE: Recent diminished painkiller effect... - 3/11/2013 10:30:56 PM   
Duskypearls


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quote:

ORIGINAL: Lynnxz

10-325? Hopefully?


Yep.

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RE: Recent diminished painkiller effect... - 3/11/2013 10:33:49 PM   
TAFKAA


Posts: 382
Joined: 1/5/2013
Status: offline 		If you metabolise it quickly, you reduce the painkilling effect.

"Psychic" experiences are generally symptomatic of brain chemistry changes inducing perceptual distortions. These are unlikely to be affecting the metabolic rate of your liver's function but it might be worth checking out.

The other possibility is the probity of the drugs you're consuming. Either your previous dose was way higher than you thought or your current dosage is sugar pills which will induce withdrawal symptoms. I'd suggest you get your medication checked somehow.

Alternatively your liver isn't metabolising it properly so it has no opportunity to take effect. Get your liver checked.

< Message edited by TAFKAA -- 3/11/2013 10:34:06 PM >

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RE: Recent diminished painkiller effect... - 3/11/2013 10:40:04 PM   
Lynnxz


Posts: 4813
Joined: 10/3/2006
From: Atlanta
Status: offline 		One option would be to drop the Tylenol, and try XR oxycodone. It's generally used for people who have built up a tolerance. (Which you have... You can't just take narcotics for years and NOT build one up.)

Another option would be to detox and start over.

I doubt your liver is an issue. People with liver dysfunction process it out slower, not faster.

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RE: Recent diminished painkiller effect... - 3/11/2013 11:06:11 PM   
FrostedFlake


Posts: 3084
Joined: 3/4/2009
From: Centralia, Washington
Status: offline 		Without contradicting Awareness, I'd like to mention some of the same things in a little different way.

Do you take and have you changed any other drugs, including nonprescription drugs, that might be interacting with this one?

Drug interactions : Percoset

Are the drugs in your kit now expired? Are they actually the drugs prescribed? I mean, do the pills match the description of them printed on the label next to the name and dose of the drugs? The withdrawal symptoms can be taken to indicate the absence of the drug. If so, that should be pretty easy to nail down.

If it turns out you are taking the drug and it is not working, Oh Shit! That indicates a metabolism issue that should be looked for, and at, right away.

I'd go on, but I don't want to muddle my points.

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RE: Recent diminished painkiller effect... - 3/12/2013 9:58:07 AM   
kdsub


Posts: 12180
Joined: 8/16/2007
Status: offline 		I would first step back and be sure you are taking medications for the right reasons. You did not say, and it is none of my business, why you were taking the drugs. It could be the problem you are taking the drugs for, is increasing in severity or simply a reaction to the powerful oxycodone.

I would say, not being a doctor, that vicoden would be a better long term pain reliever...Pecocet to me at least is a short term pain reliever with a much higher chance of addiction.

Go to your doctor...you will not find competent answers here with us.

Butch

< Message edited by kdsub -- 3/12/2013 10:14:42 AM >

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RE: Recent diminished painkiller effect... - 3/12/2013 7:38:31 PM   
LookieNoNookie


Posts: 12216
Joined: 8/9/2008
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quote:

ORIGINAL: Duskypearls

quote:

ORIGINAL: TAFKAA

What exactly are you taking?


Percocet w/acetominophen.

There have been great changes in my life, recently, in regards to mental, emotional, spiritual aspects, as well as work and how I output energy there. Most unusual is a tremendous increase in psychic experiences, in terms of their frequency and nature.

I seem to nearly be a completely different person than I was 4 months ago, using tremendous amounts of energy, on all of the above-mentioned aspects. There is a HUGE spiritual change going on in me.

I do not know what else to attribute it to. As I said, I've had years of experience w/such drugs, including tolerance issues and actual cold turkey withdrawal issues, tho' not on a daily basis when I'm presently taking between 40-100 mg/day.

It's terribly difficult for me to describe how different the recent drug inefficiency aspect is. Wish I could do better. I would normally take 40-60 mg/day, and that would do the trick. Now, even 100mg, even in one dose, doesn't have any effect, and then there's withdrawal symptoms on top of it. That should not be. Something wierd's going on.


I suspect it IS a tolerance issue.

I took that drug 26 years ago (not prescribed)....took a few nice little trips down to lil' ol' Mehico, came back with a wonderful little stash and was taking maybe 10+ of 'em a day.

After about a week or so I needed about 12, then 15 and so on.

Eventually, 25 didn't even make a dent.

Thankfully I was never the type that ever got hooked on anything...I just had my fun and then a few weeks into any one of the 3 or 4 dozen stupid things I ingested in my system...I stopped, looked back on a fun time and that was that.

Today I don't take anything stronger than aspirin, to the point that I told my doctor about 10 years ago "unless you see a bone sticking out of my shoulder or an eyeball hanging outside where it doesn't belong, don't prescribe me anything that I can't buy myself at Walgreens". (Damn bastard has kept his word all this whole time dammit).

My suggestion hon is, ask your doc for a change up....try something else for a while.

I don't know what type of pain you have but, while I know too much of this stuff is bad for your kidneys (or maybe it's the liver), Ibuprofen in enough quantity is an AMAZING pain killer....works wonders for just about everyone.

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RE: Recent diminished painkiller effect... - 3/12/2013 8:12:05 PM   
Notsweet


Posts: 873
Joined: 6/11/2006
Status: offline 		Dusky, I've got chronic pain and an considering going to get acupuncture. Have you tried that and if so, did you have any luck?

Pain management. The only illness left that's against the law to treat.

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RE: Recent diminished painkiller effect... - 3/12/2013 8:25:06 PM   
OsideGirl


Posts: 14449
Joined: 7/1/2005
From: United States
Status: offline 		I will say: Since hitting peri-menopause, pain killers are not as effective as they were. And I take them maybe two days a months, so it shouldn't be a tolerance build up.

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RE: Recent diminished painkiller effect... - 3/12/2013 9:28:09 PM   
Notsweet


Posts: 873
Joined: 6/11/2006
Status: offline 		Haven't tried anything except ibuprofen or aleve lately. I know I need to switch off, but I have a bad reaction to narcotics, and I never thought they did all that much. Figured they were there to make me too stupid to get up and reinjure myself, mostly, but it still hurt.

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RE: Recent diminished painkiller effect... - 3/13/2013 7:34:27 PM   
littlewonder


Posts: 15659
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quote:

ORIGINAL: TAFKAA

If you metabolise it quickly, you reduce the painkilling effect.

"Psychic" experiences are generally symptomatic of brain chemistry changes inducing perceptual distortions. These are unlikely to be affecting the metabolic rate of your liver's function but it might be worth checking out.

The other possibility is the probity of the drugs you're consuming. Either your previous dose was way higher than you thought or your current dosage is sugar pills which will induce withdrawal symptoms. I'd suggest you get your medication checked somehow.

Alternatively your liver isn't metabolising it properly so it has no opportunity to take effect. Get your liver checked.


This. Even my doctor has described it the same way when I've had such issues with my sleeping meds. I've built up a tolerance where they no longer work to get me to sleep but they affect my brain in the way you describe. It's not a spiritual thing. It's a brain chemistry thing.

Talk to your doctor. She/he may have to change your doses or more likely, try another med on you. Upping it would just cause even worse psychic stuff that you feel you are going through.



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RE: Recent diminished painkiller effect... - 3/13/2013 7:48:51 PM   
Duskypearls


Posts: 3561
Joined: 8/21/2011
Status: offline 		Thanks for your good and generous input and output. I finally figured out what it was/is.

I know y'all thought it was a tolerance issue, but as I told you from the git go, after one too many horse wrecks and surgeries, narcotic painkillers and I have been on infimate terms, on and off, over the last 3.5 decades, and I know from tolerance issues only too well. I understand why y'all went that route, as it was so different from my previous experiences, I found it hard to describe it well enough to you, so you would believe I know what I'm talking about, and that is my fault, and my fault, alone.

Hint number one...if I do talk about something, you can bet your bottom dollar I have more than a tiny clue of what I'm talking about. Surely some of you have noticed I don't participate in many of the discussions here. I tend to keep it light, for the most part, and get serious with those I take close to me, and they are few and far between. No grudges held here, tho', I know you are all good hearts and only wanted the best for me, so thanks muchly for all your kind offerings. So here's the scoop:

On of my Physicians, who is also a powerful energy worker, has done quite a bit of work on, and detoxing of, me lately. It would appear my system, specifically my liver, got such a boost last month that it has been detoxing pain meds at warp speed. I was nearly eating them like candy, and I couldn't keep the stuff in me fast enough to do any good. Today I got him to take it down a few notches, and help w/removing some toxins, and I feel like a new person. Have yet to pop one, when normally by this time, I'd have met my quota.

Thank Gawd for great energy workers!

ETA...and not to worry lw, the spiritual/psychic improvements are non-related, but thanks for your concern.

< Message edited by Duskypearls -- 3/13/2013 7:53:02 PM >

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RE: Recent diminished painkiller effect... - 3/13/2013 8:04:08 PM   
TheHeretic


Posts: 19100
Joined: 3/25/2007
From: California, USA
Status: offline 		You can always wash them down with booze.

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RE: Recent diminished painkiller effect... - 3/13/2013 8:16:01 PM   
Duskypearls


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Joined: 8/21/2011
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quote:

ORIGINAL: TheHeretic

You can always wash them down with booze.


Why, in Heaven's name, didn't I think of that?! Ehhhh, my Jack Daniel days are looooooong since over....like maybe about 35 years?!

Probably would'nt have helped worth a rat's ass, till I got that critter reined in a bit. I can just see me now, poppin' pills and swiggin' swill in attempts to launch those pain receptors into another universe. Yikes! Not exactly my idea of fun. At 57, one ain't exactly got the same constitution as they did at 20. It's a whole different ball game, with referees and rules that ain't very fun or fair, at times!

That's like the thought of me getting on a horse again is insane. I get hurt again, and I may not be able to get back up again, ever! Funny, too, a gal at work is trying to talk me into working one of her Paso Fino's for her in the next month or so. She thinks I'm kidding when I say I need a rockin' chair of a horse, if ever I get on any again....ya know, the kind of that'll babysit and take damned good care of you. Nope, my I guess my screwin' around days are over.

Someone please remind me of that if it sounds like I might cave on this gal's Paso. She swears he's a rocker. Oh Lawd, have mercy on my wicked, wicked soul....do not let me near a horse that calls my name!

< Message edited by Duskypearls -- 3/13/2013 8:31:48 PM >

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RE: Recent diminished painkiller effect... - 3/13/2013 8:31:42 PM   
LookieNoNookie


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quote:

ORIGINAL: Duskypearls

quote:

ORIGINAL: TheHeretic

You can always wash them down with booze.


Why, in Heaven's name, didn't I think of that?! Ehhhh, my Jack Daniel days are looooooong since over....like maybe about 35 years?!



Thank GAWD!!!!! Jack Daniels would be ENTIRELY the wrong medicine.

Crown Royal. Rocks.

(You can thank me later).

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