somethndif
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ORIGINAL: Missokyst I always wondered how people can consider oral sex not a risk for STD's. What do you think of this? Kyst Oral sex can cause throat cancer 22:00 09 May 2007 NewScientist.com news service Roxanne Khamsi People who have had more than five oral-sex partners in their lifetime are 250% more likely to have throat cancer than those who do not have oral sex, a new study suggests. The researchers believe this is because oral sex may transmit human papillomavirus (HPV), the virus implicated in the majority of cervical cancers. The new findings should encourage people to consistently use condoms during oral sex as this could protect against HPV, the team says. Other experts say that the results provide more reason for men to receive the new HPV vaccine. Maura Gillison at Johns Hopkins Bloomberg School of Public Health in Baltimore, Maryland, US, and colleagues collected blood and saliva samples from the throats of 100 patients diagnosed with cancers of the tonsils or back of the throat. The scientists also took samples from 200 healthy people for comparison. By combining the blood and saliva samples with antibody molecules, Gillison's team could tell whether a person had ever had an HPV infection. Cancer traps All of the study participants provided information about their sexual history, including the number of people with whom they had engaged in oral sex. After controlling for other risk factors for throat cancer, such as drinking and smoking, the analysis revealed that people who had prior infection with HPV were 32 times as likely to have this cancer as those with no evidence of ever having the virus. And those who tested positive for a particularly aggressive strain of the virus, called HPV-16, were 58 times more likely to have throat cancer. By comparison, either smoking or drinking increases the risk of such cancer by about threefold. The throat cancers analysed in the new study mostly started in the "crypts" of the throat – the grooves at the base of the tonsils. This might be because the tonsil grooves trap infectious particles, suggests Mark Stoler of the University of Virginia in Charlottesville, US, who was not involved in the study. High risk levels The study also revealed a link between oral sex and throat cancer caused by HPV. People who had one to five oral-sex partners in their lifetime had approximately a doubled risk of throat cancer compared with those who never engaged in this activity - and those with more than five oral-sex partners had a 250% increased risk. There was an even stronger link between oral sex and throat cancers clearly caused by HPV-16 (those tumours that tested positive for the strain). People with more than five oral sex partners had a 750% increased risk of these HPV-16-caused cancers. "This study is important because it is putting all of the pieces together," says Gillison. "We need to add oral HPV infection to the list of risks for oral cancer," she adds. Virus vaccine A vaccine against several of the most aggressive strains of HPV linked to cervical cancer received approval from the US Food and Drug Administration in 2006. However the plan to vaccinate adolescent girls with this vaccine developed by Merck, called Gardasil, has received some criticism. There have been no studies investigating whether the vaccine can also protect against throat cancer, but the new evidence linking HPV to throat cancer could lead to broader vaccination with Gardasil. "We will see a push for vaccination in men," says Stoler, who has been involved in the development of the vaccine. Tonsil and throat cancers affect about two in every 100,000 adults in the US. The new results could promote the development of spit tests for HPV infection to help identify people at high risk for these cancers, researchers say. Journal reference: New England Journal of Medicine (vol 356, p 1944) http://www.newscientist.com/article/dn11819-oral-sex-can-cause-throat-cancer.html I think you need to keep all this in perspective. At the end of this article it says that throat and tonsil cancers affect 2 of every 100,000 adults in this country. So, if people who have had more than 5 oral sex partners have a 250% increased risk of throat cancer, that means that of 100,000 such persons with more than 5 oral sex partners over their lives, that 5, instead of 2, of those 100,000 will get throat cancer. For those with HPV-16, the most serious strain of HPV, the study says there is a 750% increased risk of throat cancer. HORRORS!!! But that means that of those with the HPV-16 virus and more than 5 oral sex partners, 15, instead of 2, of every 100,000 persons with HPV-16 will get throat cancer. Conversely, it also means that 99,985 of those oral sex addicts with HPV-16 will not get throat cancer! I don't think this "increased" risk is something to lose much sleep over. Dan
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